HOW HEMP INTERACTS WITH OUR BODY

 The Endocannabinoid System

The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found in cannabis. Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including sleep, mood, appetite, memory, reproduction, and fertility.

The ECS exists and is active in your body even if you do not use cannabis.

The ECS involves three core components: endocannabinoids, receptors, and enzymes.

 Endocannabinoids

Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They are similar to cannabinoids, but they’re produced by your body. Experts have identified two key endocannabinoids so far: anandamide (AEA) and 2-arachidonoylglyerol (2-AG). These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each.

  Endocannabinoid receptors

These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors:

CB1 receptors, which are mostly found in the central nervous system.

CB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells.

Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to. For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain. Others might bind to a CB2 receptor in your immune cells to signal that your body’s experiencing inflammation, a common sign of autoimmune disorders.